Buchwald Hartwig diversification of unprotected halotryptophans, halotryptophan containing tripeptides and the natural product barettin in aqueous conditions

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REFERENCE Renault, Yohann JG; Lynch, Rosemary; Marelli, Enrico; Sharma, Sunil V; Pubill-Ulldemolins, Cristina; Sharp, Joshua A; Cartmell, Christopher; Cárdenas, Paco; Goss, Rebecca JM (2019). Chemistry Communications. https://doi.org/10.1039/c9cc02554e. ABSTRACT Blending synthetic biology and synthetic chemistry represents a powerful approach to diversity … Read More

Heck diversification of indole-based substrates under aqueous conditions: From indoles to unprotected halo-tryptophans and halo-tryptophans in natural product derivatives

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REFERENCE Pubill-Ulldemolins, Cristina; Sharma, Sunil V; Cartmell, Christopher; Zhao, Jinlian; Cárdenas, Paco; Goss, Rebecca JM (2019). Chemistry – A European Journal. https://doi.org/10.1002/chem.201901327. ABSTRACT The blending of synthetic chemistry with biosynthetic processes provides a powerful approach to synthesis. Biosynthetic halogenation and … Read More